Changes and Role of Serum Gastrin in Early Diagnosis of Abdominal Type of Henoch-Schönlein Purpura Children

  • Li Ping Yuan
  • Kai Cheng
  • Ya Nan Wang
  • Ming Gui
  • Bo Hu

Abstract

Early and accurate diagnosis of Henoch-Schönlein purpura (HSP) is important when abdominal symptoms precede the onset of characteristic palpable purpura. This study was to investigate serum gastrin-17 changes in HSP with gastrointestinal symptoms to determine if gastrin-17 was helpful to the early diagnosis of HSP. The results showed serum gastrin-17 in HSP patients with abdominal symptoms was obviously decreased, which was significantly negative correlated with the abdominal score. HSP patients in boys had lower gastrin-17 level than girls, especially the boys with late purpura. Gastrin-17 may provide a clue to the early diagnosis of HSP presenting predominantly with abdominal symptoms.

Published
2017-12-10
How to Cite
YUAN, Li Ping et al. Changes and Role of Serum Gastrin in Early Diagnosis of Abdominal Type of Henoch-Schönlein Purpura Children. Current Science, [S.l.], v. 113, n. Issue 7, dec. 2017. ISSN 0011-3891. Available at: <http://currentscience.org/index.php/CS/article/view/178>. Date accessed: 20 apr. 2018.